Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine BMP-2. 96wells/kit, with removable strips.
免疫原
Expression system for standard: CHO; Immunogen sequence: Q283-R396
交叉反应
There is no detectable cross-reactivity with other relevant proteins.
敏感性
<2pg/ml
检测范围
31.2pg/ml-2000pg/ml
基因名称
BMP2
基因全名
bone morphogenetic protein 2
Uniprot ID
C8C060
指标别名
Bone morphogenetic protein 2 ;BMP2 ;
背景资料
Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant Pig porcine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.
◆ 0.01M TBS: Add 1.2g Tris, 8.5g Nacl; 450μl of purified acetic acid or 700μl of concentrated to 1000ml H2O and adjust pH to 7.2-7.6. Finally, adjust the total volume to 1L.
◆ 0.01M PBS: Add 8.5g sodium chloride, 1.4g Na2HPO4 and 0.2g NaH2PO4 to 1000ml distilled water and adjust pH to 7.2-7.6. Finally, adjust the total volume to 1L.