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A synthetic peptide corresponding to a sequence at the N-terminus of human Connexin 37(3-17aa DWGFLEKLLDQVQEH), identical to the related mouse and rat sequences.
Rabbit IgG
Lyophilized
12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
单克隆
Human,Mouse,Rat
Rabbit
现货
博士德生物
WB,IHC-P,ICC
500ug/ml
50ul/100ul/150ul
规格: | 50ul | 产品价格: | ¥860.0 |
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规格: | 100ul | 产品价格: | ¥1520.0 |
规格: | 150ul | 产品价格: | ¥2280.0 |
货号 | BA3314 |
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产品名称 | ANTI-GJA4 Antibody |
基因名 | GJA4 |
抗体来源 | Rabbit |
克隆 | Polyclonal |
抗体亚型 | Rabbit IgG |
分子量 | 37KD |
免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Connexin 37(3-17aa DWGFLEKLLDQVQEH), identical to the related mouse and rat sequences. |
内容 | 500ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA |
纯化方式 | Immunogen affinity purified. |
浓度 | 500ug/ml |
产品形态 | Lyophilized |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Gap junction alpha-4 protein(GJA4), also called CX37 is a protein that in humans is encoded by the GJA4 gene. This gene is mapped to 1p34.3. This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. CX37 had been shown to reflect the stage and maturity of luteinized follicles in animal studies. |
研究类别 | 1. Tsai, M.-Y., Lan, K.-C., Huang, K.-E., Huang, F.-J., Kung, F.-T., Chang, S.-Y. Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. Fertil. Steril. 80: 1437-1443, 2003.2. Wong, C. W., Christen, T., Roth, I., Chadjichristos, C. E., Deroutte, J.-P., Foglia, B. F., Chanson, M., Goodenough, D. A., Kwak, B. R. Connexin37 protects against atherosclerosis by regulating monocyte adhesion. Nature Med. 12: 950-954, 2006.3. Yamada, Y., Izawa, H., Ichihara, S., Takatsu, F., Ishihara, H., Hirayama, H., Sone, T., Tanaka, M., Yokota, M. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. New Eng. J. Med. 347: 1916-1923, 2002. |
Uniprot ID | GJA4: P35212 |
推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。 |
为了提供最优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot: | 1:500-2000 |
Immunohistochemistry(Paraffin-embedded Section): | 1:50-400 |
Immunocytochemistry: | 1:50-400 |
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
*最优稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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