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- MedChemExpress(MCE)
- 美国
- HY-U00198
- 2025年12月05日
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- 技术资料
- 保存条件：
Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名：
Win 17665
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
60607-35-4
- 规格：
1 mg
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Topterone
CAS No. : 60607-35-4
MCE 国际站：Topterone
产品活性：Topterone 是一种局部抗雄激素。
研究领域：Vitamin D Related/Nuclear Receptor
作用靶点：Androgen Receptor
In Vivo: Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ.
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