BPH-652

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BPH-652

CAS No. : 157124-84-0

MCE 国际站：BPH-652

产品活性：BPH-652 是 CrtM 的抑制剂，K_i 值为 1.5 nM，IC₅₀ 值为100-300 nM (S. aureus 色素形成)。

研究领域：Others

作用靶点：Others

In Vivo: BPH-652 treatment (0.5 mg twice per day (days −1, 0, 1, and 2), Intraperitoneal injection) significantly lowers S. aureus bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.

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