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- 2025年12月05日
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- 保存条件：
-20°C, protect from light
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
69981-39-1
- 规格：
100 mg
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Bis-Tos-(2-hydroxyethyl disulfide)
CAS No. : 69981-39-1
MCE 国际站：Bis-Tos-(2-hydroxyethyl disulfide)
产品活性：Bis-Tos-(2-hydroxyethyl disulfide) 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。
研究领域：Antibody-drug Conjugate/ADC Related
作用靶点：ADC Linker
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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文献和实验Disulfide Conjugation of Peptides to Oligonucleotides and Their Analogs
of oligonucleotides and their analogs is being studied widely towards improving the delivery of oligonucleotides into cells. Amongst the many possible routes of conjugation, the disulfide linkage has proved to be the most popular. This reversible linkage
Gene Transfer into Mammalian Cells Using Calcium Phosphate and DEAE-Dextran
, especially use of N,N-bis (2-hydroxyethyl)-2-aminoethanesulfonic acid (the BES variation), has proven to be the only method sufficient for the cotransfection of multiple plasmids into a wide variety of cell types. Although not as widely used today, DEAE
. Buffer Mw pKa 20o C Working range delta pKa per 10o C MES 2-(N -morpholino)ethanesulfonic acid 195.2 6.15 5.5-6.7 -0.110 Bis-Tris bis (2-hydroxyethyl)iminotris (hydroxymethyl)methane 209.2 6.5 5.8-7.2 ADA N -(2-acetamido
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