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Boc-amino-PEG3-SSPy
MCE 国际站:Boc-amino-PEG3-SSPy
产品活性:Boc-amino-PEG3-SSPy 是一种可降解 (cleavable) 的含 3 个单元 PEG 的 ADC linker,可用于合成抗体偶联活性分子 (ADC)。
研究领域:Antibody-drug Conjugate/ADC Related
作用靶点:ADC Linker
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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文献和实验Synthesis of Peptides Using Tert-Butyloxycarbonyl (Boc) as the -Amino Protection Group
The use of the tert -butyloxycarbonyl (Boc) as the N α-amino protecting group in peptide synthesis can be advantageous in several cases, such as synthesis of hydrophobic peptides and peptides containing ester and thioester moieties
Methylated Polyamines as Research Tools
resulted in corresponding di-Boc-amines, which after deprotection gave target β- and γ-MeSpd’s. To prepare α-MeSpd, the starting compound, 3-amino-1-butanol, was converted into N -Cbz-3-amino-1-butyl methanesulfonate, which alkylated putrescine
in size and shape but show variations in aromatic, electrostatic, and hydrogen bonding properties. These variations provide opportunities to study properties of importance for amide bond mimicry. The derivatives are synthesized from protected natural amino
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