溶血二氢鞘磷脂|lyso-Dihydrosphingomye

溶血二氢鞘磷脂，lyso-Dihydrosphingomyelin，lyso-Dihydrosphingomyelin

产品名称：溶血二氢鞘磷脂-lyso-Dihydrosphingomyelin

产品货号：1913-1

产品规格：1mg

背景资料：This product is the saturated form of the more plentiful sphingomyelin, a lipid that is found in mammalian cell membranes, especially in the membranes of the myelin sheath, and is the most abundant sphingolipid in mammals. Dihydrosphingomyelin has been identified as a minor lipid component in many mammalian tissues but has recently been reported to be present in significant amounts in bovine brain and bovine milk.1 It is also found in much greater amounts in human lens membranes (half of all the phospholipids) where it has a critical role in ocular function and perhaps in age-related nuclear cataracts.2 However, dihydrosphingomyelin has been reported to occur only in small amounts in the lens membranes of other mammals. Dihydrosphingomyelin demonstrates good mixing properties with both sterols and sphingomyelin indicating that it could function as a membrane organizer and this may be the reason it is present in large amounts in human lens membranes where cholesterol is also enriched.3 The enzyme sphingomyelinase is active towards dihydrosphingomyelin and readily converts it to dihydroceramide. Recent evidence has been presented that indicates that dihydrosphingomyelin impairs HIV-1 infection by rigidifying liquid-ordered membrane domains, a finding that could have great potential in providing a therapeutic treatment for this debilitating disease.4

保存建议：溶血二氢鞘磷脂-lyso-Dihydrosphingomyelin对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：Dihydrosphingosylphosphorylcholine, (mixture of D-erythro and L-threo isomers)

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