N-十六烷酰基-乳糖基神经酰胺|N-Hexadecanoyl

N-十六烷酰基-乳糖基神经酰胺，N-Hexadecanoyl-lactosylceramide，N-Hexadecanoyl-lactosylceramide

产品名称：N-十六烷酰基-乳糖基神经酰胺-N-Hexadecanoyl-lactosylceramide

产品货号：1532-1

产品规格：1mg

背景资料：This well-defined lactosylceramide is ideal for biological studies and comparisons to natural lactosylceramides.1 Lactosylceramide is the precursor of many other glycosphingolipids and also functions as a second messenger and protein receptor, making it a very important organic molecule. Many cellular processes are dependent on lactosylceramide since it is the substrate for neutral oligoglycosylceramides and gangliosides, all of which have their own vital functions. Lactosylceramide also helps to stabilize the lipid membrane, activate receptor molecules and acts as a receptor for certain bacteria and toxins. In animals, where it is found mostly in epithelial and neuronal cells, it is expressed on neutrophils and macrophages where it binds to toxins and bacteria, which are then engulfed and eliminated. Its role as a second messenger has been found to be vital and dysfunctions in its processes can lead to cancer and inflammation since it is critical to neutrophil activity and in activating anti-inflammatory responses.2 Therefore, it is being studied for its use in cancer therapies and as a therapy for other diseases. Other examples of lactosylceramide second messenger functions are tumor necrosis factor and platelet-derived growth factor. A deficiency in the enzyme responsible for hydrolyzing the galactose of lactosylceramide leads to lactosylceramidosis, which is characterized by an accumulation of lactosylceramide that causes a primary neurological disorder.3 Lactosylceramide is also important in the activation of platelet/endothelial cell adhesion molecule-1 which causes adhesion and diapedesis of monocytes/lymphocytes.4

保存建议：N-十六烷酰基-乳糖基神经酰胺-N-Hexadecanoyl-lactosylceramide对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：N-C16:0-Lactosylceramide|N-Palmitoyl-lactosylceramide

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