- 询价
- 近岸蛋白(Novoprotein)
- DRA48
- 2025年12月02日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant 2019-nCoV S2 Protein (C-Fc)
- 保存条件：
Reconstituted protein solution should be stored at ≤ -20°C.
- 规格：
1mg
Recombinant 2019-nCoV S2 Protein (C-Fc)
Catalog #: DRA48 Derived From: Human Cells
Description:
Recombinant 2019-nCoV S2 Protein is produced by our Mammalian expression system with a Fc tag at the C-terminus.
Accession: QHD43416.1
Names(Known as): S2 protein; Spike glycoprotein Subunit2; S glycoprotein Subunit2; Spike protein S2; COVID-19
Quality Control:
Mol Mass: 84.1kDa AP Mol Mass: 100-130kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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文献和实验Transient Production of scFv-Fc Fusion Proteins in Mammalian Cells
cells HEK293T and suspension HEK293-6E cells. More than 10 �g/mL yield of scFv-Fc protein can be obtained every day for one to two weeks by transient production in HEK293T cells, whereas soluble HEK293-6E cells produce more than 100 �g/mL scFv-Fc protein
Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation. Given that PC is one of the major naturally
为肌肉调节蛋白质。分子量约 14万，在肌原纤维 A带中的 A丝上，显示 43纳米周期，常混存于肌球蛋白的材料中。为 G． Offer（ 1972）所发现。
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