5-Aminouridine,2149-76-0

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5-Aminouridine

CAS No. : 2149-76-0

MCE 国际站：5-Aminouridine

产品活性：5-Aminouridine 可以修饰核碱基并且可以掺入靶 DNA 中。5-Aminouridine 表现出广泛的生物活性，可抑制肿瘤，真菌和病毒的生长。

研究领域：Anti-infection

作用靶点：Fungal  |  Influenza Virus

In Vitro: This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)₃³⁺. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites.

In Vivo: 5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [³²P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma.

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