Lanreotide,2378114-72-6

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Lanreotide acetate

CAS No. : 2378114-72-6

MCE 国际站：Lanreotide acetate

产品活性：Lanreotide acetate (BIM 23014 acetate) 是一种具有抗肿瘤活性的生长抑素类似物。Lanreotide acetate 可用于类癌综合症。

研究领域：Others

作用靶点：Others

In Vitro: Lanreotide acetate (BIM 23014 acetate) (24-48 hours; 100  nM; GH3 cells) combines with radiation increasing in apoptotic sub-G1 proportion.
Lanreotide acetate results in a dose-dependent decrease in GH3 cell colony forming units. Lanreotide acetate at doses of 1, 10, 100, and 1000 nM results in cell survival rates of 75, 56, 39 and 27% respectively. The IC50 (50% inhibition of cell growth) was 57 nM.
Lanreotide acetate inhibits GH-secreting pituitary adenoma cell proliferation and hormone release in vitro.

In Vivo: Lanreotide acetate (2.5-10mg/kg; s.c.; daily for 5 days) resluts in tumor growth inhibition.

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