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- 保存条件:
4°C, sealed storage, away from moisture and light
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货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
10 mM * 1 mL/1 mg/5 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥4953.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥2040.0 |
| 规格: | 5 mg | 产品价格: | ¥5100.0 |
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BTK inhibitor 10
CAS No. : 2241732-30-7
MCE 国际站:BTK inhibitor 10
产品活性:BTK inhibitor 10 是一种有效的口服活性 Bruton kinase (BTK) 抑制剂,摘自专利 WO2018145525,例 33。BTK inhibitor 10 有潜力用于类风湿关节炎的研究。
研究领域:Protein Tyrosine Kinase/RTK
作用靶点:Btk
In Vivo: BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33.
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文献和实验Purification of Inhibitor-Free Soil DNA Obtained by other Methods
tube (not supplied). Add 30-100 μl Elution Buffer directly onto the center of HiBind® matrix. Incubate at 65°C for 10-15 minutes. 13. Centrifuge at full speed (13,000 x g) for 1 min to Elute DNA. 14. Repeat elution step 12-13
Ribonuclease inhibitor (RI) is a cytoplasmic protein of ∼50 kDa that tightly binds and inhibits ribonucleases (RNases) from the pancreatic superfamily (1 ). Diverse RNases with very limited sequence similarities, including RNase
for cell lysis: 10 mM Tris-HCl, pH 7.4,50 mM NaCl, 5 mM EDTA, 50 mM NaF, 30 mM Na 4 P 2 O 7 ,and 1% (v/v) Triton-X100. 5. Protease inhibitors and phosphatase inhibitor are added fresheach time with the following final concentrations: 10 μg/mLaprotinin
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