- ¥1880 - 2880
- 百奥莱博
- JN1287-DRY
- 北京
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
120
- 英文名：
Recombinant Human Cadherin-16
- 保质期：
长期
- 供应商：
北京百奥莱博科技有限公司
- 保存条件：
冻干蛋白置于-20℃以下可长期保存，室温
- 规格：
10μg|50μg|500μg|1mg
特别提示：包括重组人Cadherin-16(CDH16)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：重组人Cadherin-16(CDH16)
英文名称：Recombinant Human Cadherin-16
产品货号：JN1287
产品规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Pro18-Ala786在C端含有His标签。
CDH16质量控制：＞95%(还原性SDS-PAGE)
CDH16制剂：冻干品
CDH16保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。
CDH16复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。
关于CDH16：
Cadherin-16(CDH16) is a single-pass type I membrane protein which contains six cadherin domains. Mature cadherin proteins consist of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium-dependent cell adhesion proteins and may contribute to the sorting of heterogeneous cell types. They preferentially interact with themselves in a homophilic manner in connecting cells. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development. CDH16 is composed of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain. However, it lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.
除了重组人Cadherin-16(CDH16),，我公司还供应以下相关产品：
| 货号 | 名称 | 规格 |
| JN0207 | 重组人GM-CSF(哺乳动物表达)(含His标签) | 10μg|50μg|500μg|1mg |
| JN0334 | 重组人白介素IL-6(白细胞介素6) | 10μg|50μg|500μg|1mg |
| JN0409 | 重组人白介素IL-2Rγ(白细胞介素2Rγ) | 10μg|50μg|500μg|1mg |
| JN1929 | 重组人脂肪酸结合蛋白1(FABP1) | 10μg|50μg|500μg|1mg |
| JN1978 | 重组人血管生成素(Angiogenin) | 10μg|50μg|500μg|1mg |
| JN0840 | 重组人FLT3LG(FMS样酪氨酸激酶3配体) | 10μg|50μg|500μg|1mg |
| JN0882 | 重组人信号转导与转录激活因子5B(STAT5B) | 10μg|50μg|500μg|1mg |
| JN0932 | 重组人FIBP(FGFIBP)(酸性成纤维细胞生长因子胞内结合蛋白) | 10μg|50μg|500μg|1mg |
| JN0969 | 重组人α-突触核蛋白(α-Synuclein)(SNCA) | 10μg|50μg|500μg|1mg |
| JN0988 | 重组人胞质磺基转移酶家族1B成员1(SULT1B1) | 10μg|50μg|500μg|1mg |
| JN1073 | 重组人MGMT(O6-甲基鸟嘌呤-DNA甲基转移酶) | 10μg|50μg|500μg|1mg |
| JN1084 | 重组人(富含亮氨酸的α-2-糖蛋白)LRG1 | 10μg|50μg|500μg|1mg |
| JN1137 | 重组人聚集素(Clusterin) | 10μg|50μg|500μg|1mg |
| JN1460 | 重组小鼠TGF-beta RII(C端带Fc标签) | 10μg|50μg|500μg|1mg |
| JN1544 | 重组人吲哚胺-2,3双加氧酶(IDO) | 10μg|50μg|500μg|1mg |
| JN1621 | 重组小鼠BTN1A1(嗜乳脂蛋白亚家族1成员A1) | 10μg|50μg|500μg|1mg |
| ZN1604 | 人COL4A3重组蛋白 | 100ng |
| ZN1800 | 大鼠CT-1重组蛋白 | 100ng |
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文献和实验满足以上步骤中对温度和时间的要求）。取出容器，室温冷却 10~20 分钟（注意：不可将切片从缓冲液中取出冷却，以便使蛋白能够恢复原有的空间构型）。 PBS 洗，下接免疫组化染色步骤。适用的抗原有：AR，Bax，Bcl-2，C-fos，X-jun，C-kit，C-myc，E-cadherin，Chromogranin A，Cyclin，ER，Heat shock protein，HPV，Ki-67，MDMZ，p53，p34，p16，p15，P-glycoprotein，PKC，PR，PCNA，ras
DNA Methylation Analysis in Human Cancer
Many tumor suppressor genes (such as p16, Rb, VHL, E-cadherin , and hMLH1 ) that are silenced by mutation are also inactivated by gene silencing through DNA methylation. Characterization of genes hypermethylated in human cancers but not in normal
A PCR-Based Method for Studying DNA Methylation
may become methylated upon oncogenic transformation. These alterations in the methylation profile are correlated with silencing of tumor suppressor genes such as p15, p16, Rb, VHL, e-cadherin, ER, and HIC1 (8 ).
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