重组人Neuroserpin北京品牌

特别提示：包括重组人Neuroserpin在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人Neuroserpin
英文名称：Recombinant Human Neuroserpin
产品货号：GS4631
产品规格：5μg

分子量：Approximately 44.7kDa,a single non-glycosylated polypeptide chain containing 394 amino acid residues.
储存条件：冷冻（-20℃）

概述

Neuroserpin encoded by the SERPINI1 gene in humans is a member of the serine proteinase inhibitor(serpin)family.It reacts preferentially with tissue-type plasminogen activator(tPA).Neuroserpin is expressed mainly in the central nervous system(CNS)in response to neuronal depolarization and plays an important role in the development of synaptic plasticity.Mutations in human neuroserpin result in a form of autosomal dominant inherited dementia which is characterized by the presence of intraneuronal inclusion bodies and is known as Familial Encephalopathy with Neuroserpin Inclusion Bodies.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.5μg/ml,corresponding to a specific activity of>2000 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuNeuroserpin as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	TGATFPEEAI ADLSVNMYNR LRATGEDENI LFSPLSIALA MGMMELGAQG STQKEIRHSM GYDSLKNGEE FSFLKEFSNM VTAKESQYVM KIANSLFVQN GFHVNEEFLQ MMKKYFNAAV NHVDFSQNVA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF KGNWKSQFRP ENTRTFSFTK DDESEVQIPM MYQQGEFYYG EFSDGSNEAG GIYQVLEIPY EG

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