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- 2026年01月22日
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文献和实验Hantzsch Based Macrocyclization Approach for the Synthesis of Thiazole Containing Cyclopeptides
An innovative macrocyclization approach via high-yielding solid-phase intramolecular thioalkylation reaction is described. The reaction of S -nucleophiles with newly generated N-terminal 4-chloromethyl thiazoles leads
DETECTION OF ß-GALACTOSIDASE AND ALKALINE PHOSPHATASE ACTIVITIES IN TISSUE
1954, Pearson et al 1963). The most common such substrate is an indole derivative, 5-bromo-4-chloro-3-indolyl-ß-D-galactoside (X-gal, Holt and Sadler, 1958). When ß-gal cleaves the glycosidic linkage in X-gal, a soluble, colorless indoxyl monomer
Conjugation of 5′‐Functionalized Oligodeoxyribonucleotides with Properly Functionalized Ligands
Halogenoalkylated acridine, psoralen, orthophenanthroline, or thiazole orange (unit 4.8 , structures 1e, 2f, 3c, and 4e, respectively) 2‐Pyridyldisulfide psoralen (unit 4.8 , structure 2h
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