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文献和实验Treatment of SCCVII Tumors with Systemic Chemotherapy and Interleukin-12 Gene Therapy Combination
Cyclophosphamide and Interleukin-12 (IL-12) have been successfully used in clinical trials for treating malignancies. In this study, we explore the coadministration of cyclophosphamide and IL-12 plasmid DNA followed by electroporation
的使用,耐受性相当良好,不良反应非常少见,副作用则是对视网膜的毒性,所以应定期做眼科的检查。 Cyclophosphamide:高剂量静脉注射疗法广泛应用在治疗狼疮病。副作用如恶心、呕吐、掉发、骨髓毒性、卵巢衰竭、无精虫症、及出血性膀胱炎等。 Azothioprine:一般认为疗效比 Cyclophosphamide 小,毒性也较小。
The In Vitro Mammalian Chromosome Aberration Test
of asymmetrical structural chromosome aberrations is measured. Human peripheral blood lymphocytes do not normally divide. The assessment of the effects of cyclophosphamide on lymphocytes, stimulated to divide in whole blood cultures in vitro, is described
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