Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
信号通路
Transmembrane Transporters
靶点
AMPA
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-
-
-
IC50
-
-
-
-
-
体外研究
Talampanel is a glutamate receptor inhibitor with anti-seizure activity.
体内研究
Talampanel reduces motoneuronal calcium in a mouse model of ALS, but its effi cacy declines as the disease progresses, suggesting that medication initiation in the earlier stages of the disease might be more effective.
临床实验
N/A
特征
N/A
相关实验数据(此数据来自于公开文献,信裕生物并不保证其有效性):
酶活性检测实验
方法
N/A
细胞实验
细胞系
N/A
浓度
N/A
处理时间
N/A
方法
N/A
动物实验
动物模型
N/A
配制
N/A
剂量
N/A
给药方式
N/A
参考文献: 1. Langan YM, et al. Epilepsia. 2003 Jan, 44(1), 46-53.
2. Paizs M, et al. Amyotroph Lateral Scler. 2011 Sep, 12(5), 340-344.
包装清单: