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- P6254-20μg
- 2025年07月14日
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- 技术资料
- 规格：
20μg
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Rat | 116562 | P17108 | E. coli | 135aa | 15.5kDa | － |
| About this Antibody | |
| Name | Recombinant Rat IL-2 (Recombinant Rat Interleukin-2; rRtIL-2)；重组大鼠白细胞介素2 |
| Synonyms | aldesleukin; Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF |
| Purity | >97% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×106IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | A 0.2μm filtered concentrated sterile solution in 10mM sodium citrate, pH4.0. |
| Endotoxin | Less than 1EU/μg of rRtIL-2 as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for Tcell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55kDa IL2Rα, 75kDa IL2Rβ, 64kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes. Recombinant rat IL-2 is a 15.3kDa protein containing 134 amino acid residues and it shares about 82%, 66%, 66%, 60% and 54% amino acid sequence identity with mouse, human, rhesus macaque, pig and equus caballus IL-2, respectively. |
| Amino Acid Sequence | APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ |
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