Recombinant Human 4-1BB Receptor/TNFRSF9

Recombinant Human 4-1BB Recept

or/TNFRSF9
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  • ¥18967
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  • 2025年08月23日
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    • 规格

      1mg

    产品编号 产品名称 产品包装 产品价格
    P5399-5μg Recombinant Human 4-1BB Receptor/TNFRSF9 5μg 646.00元
    P5399-20μg Recombinant Human 4-1BB Receptor/TNFRSF9 20μg 1613.00元
    P5399-100μg Recombinant Human 4-1BB Receptor/TNFRSF9 100μg 5925.00元
    P5399-1mg Recombinant Human 4-1BB Receptor/TNFRSF9 1mg 18967.00元
    Species Gene ID Accession Source Length MW Tag
    Human 3604 Q07011 E. coli 166aa 17.7kDa
    About this Antibody
    Name Recombinant Human 4-1BB Receptor/TNFRSF9 (Recombinant Human 4-1BB Receptor; rHu4-1BB Receptor);重组人4-1BB受体/TNFRSF9
    Synonyms CD137; ILA; TNFRSF9; 4-1BB; 4-1BB ligand receptor; CD137 antigen; CD137MGC2172; CDw137; FLJ43501; ILAhomolog of mouse 4-1BB; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
    Purity >97% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90% of inibition was seen using a concentration of 1μg for both 4-1BB Ligand and 4-1BB Receptor.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered concentrated solution in 10mM PB, pH8.0, 150mM NaCl.
    Endotoxin Less than 1EU/μg of rHu4-1BB Receptor as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background 4-1BB receptor, also named TNFRSF9 is a member of the TNF superfamily of receptors. It is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB receptor binds to 4-1BBL, and they co-stimulate activity for activated T cells. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. Crosslinking of 4-1BB Receptor enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
    Amino Acid Sequence ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS

    包装清单:

    产品编号 产品名称 包装
    P5399-5μg Recombinant Human 4-1BB Receptor/TNFRSF9 5μg
    P5399-20μg Recombinant Human 4-1BB Receptor/TNFRSF9 20μg
    P5399-100μg Recombinant Human 4-1BB Receptor/TNFRSF9 100μg
    P5399-1mg Recombinant Human 4-1BB Receptor/TNFRSF9 1mg
    - 说明书 1份

    保存条件:
    -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
    由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
    本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
    为了您的安全和健康,请穿实验服并戴一次性手套操作。

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