重组人吲哚胺-2,3双加氧酶(IDO)北京厂家

特别提示：包括重组人吲哚胺-2,3双加氧酶(IDO)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人吲哚胺-2,3双加氧酶(IDO)
英文名称：Recombinant Human Indoleamine 2,3-dioxygenase
产品货号：JN1544
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Gly403在N端含有His标签。

IDO质量控制：＞95%(还原性SDS-PAGE)

IDO制剂：液体

IDO保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于IDO：
Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.

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