- ￥5832.53
- nsjbio
- V3840SAF-100UG
- 2025年07月12日
- Mouse
- Human. Other species not tested.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A portion of amino acids 998-1104 from the human protein were used as the immunogen for this Filaggrin antibody.
- 亚型：
Mouse IgG2b, kappa
- 克隆性：
单克隆
- 适应物种：
Human. Other species not tested.
- 宿主：
Mouse
- 规格：
100 ug
Primary antibody
纯化方法：
Purified
通用信息：
1 mg/ml in 1X PBS; BSA free, sodium azide free
产品描述：
Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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