- ￥4249.59
- nsjbio
- N1094-100UG
- 2025年07月07日
- Rabbit
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.
- 亚型：
Rabbit IgG
- 适应物种：
Human, Mouse
- 宿主：
Rabbit
- 规格：
100 ug
Primary antibody
纯化方法：
Purified
通用信息：
0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产品描述：
PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.
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文献和实验Retrofitting BACs and PACs With LoxP Transposons to Generate Nested Deletions
. Because substantial quantities of high-quality clone DNA can be easily prepared from BACs and PACs, they are also potentially valuable reagents for direct use in biologic experiments that seek to functionally evaluate the sequences contained
A Transgenic Approach to Studying Imprinted Genes: Modified BACs and PACs
The advantages of using large genomic clones in the analysis of imprinted genes is described in Chapter 4 with particular reference to yeast artificial chromosomes (YACs). These contain on average 500-600 kb of DNA but can be much larger (>1 Mb
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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