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PREPL Antibody (C-term) [APR05

656G]
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  • ¥1375 - 5000
  • Leading Biology
  • APR05656G
  • 美国
  • 2025年10月01日
  • WB, IHC-P
  • Rabbit
  • H, Ha, M
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 靶点

      Prolyl endopeptidase-like, 3421-, Prolylendopeptidase-like, PREPL, KIAA0436

    • 浓度

      Affinity Purification

    • 应用范围

      WB, IHC-P

    • 宿主

      Rabbit

    • 适应物种

      H, Ha, M

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 克隆性

      Polyclonal

    • 保存条件

      Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    • 形态

      Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

    • 免疫原

      This PREPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-652 amino acids from the C-terminal region of human PREPL.

    • 规格

      400 µl/200 µl/100 µl/50 µl

    规格:400 µl产品价格:¥5000.0
    规格:200 µl产品价格:¥3250.0
    规格:100 µl产品价格:¥2250.0
    规格:50 µl产品价格:¥1375.0
    分子量:83927

    细胞定位:Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q8C167}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8C167}. Golgi apparatus {ECO:0000250|UniProtKB:Q8C167}. Nucleus Note=Co-localizes with AP-1 in the trans-Golgi network (By similarity) Co-localizes with MAP2 and ACTB on the cytoskeleton (By similarity) Co-localizes with STX6 and GOSR2 at the Golgi apparatus (By similarity). {ECO:0000250|UniProtKB:Q8C167}

    功能:Serine peptidase whose precise substrate specificity remains unclear (PubMed:16143824, PubMed:16385448, PubMed:28726805). Does not cleave peptides after a arginine or lysine residue (PubMed:16143824). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (PubMed:23321636). May play a role in the regulation of synaptic vesicle exocytosis (PubMed:24610330).

    总结:Tissue Location: Expressed in pyramidal neurons of the temporal cortex and neocortex (at protein level) (PubMed:23485813). Widely expressed (PubMed:15913950, PubMed:16385448). Expressed at higher level in brain, skeletal muscle, heart and kidney (PubMed:15913950, PubMed:16385448). Expressed at the endplates in the neuromuscular junction (PubMed:24610330).

    稀释方法:WB--1:1000 IHC-P--1:100~500

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