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文献和实验TRAF‐Mediated TNFR‐Family Signaling
Keywords: TNF family; TNFR family; IL?1R/TLR; TRAF proteins; signal transduction; inflammation GO TO THE FULL PROTOCOL: PDF or HTML at Wiley Online Library
Genetic Engineering in the Mouse: Tuning TNF/TNFR Expression
With the exponential increase in the number of genes identified by various genome projects, it has become imperative that efficient methods be developed for deciphering gene function. Genetically engineered strains of mice are now critical
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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