- $495
- Leading Biology
- United States
- AMM05576G
- 2026年03月31日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 库存：
100
- 宿主：
Rabbit
- 靶点：
Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PLEKHG5 (45%).
- 规格：
50 μg
57kDa
细胞定位：
Antigen Cellular Localization: Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes
形式：
Liquid
参考文献：
Ramarao C.S.,et al.J. Biol. Chem. 267:21936-21945(1992). Forray C.,et al.Mol. Pharmacol. 45:703-708(1994). Schwinn D.A.,et al.J. Pharmacol. Exp. Ther. 272:134-142(1995). Wright C.D.,et al.Circ. Res. 103:992-1000(2008). Wright C.D.,et al.Cell. Signal. 24:794-802(2012).
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADRA1B antibody (C-Terminus).
功能：
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
总结：
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
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文献和实验Modification of the 5′ Terminus of Oligonucleotides for Attachment of Reporter and Conjugate Groups
terminus of synthetic oligonucleotides. Tetrahedron Lett. 27:3991‐3994. Cumber, J.A., Forrester, J.A., Foxwell, B.M., Ross, W.C., and Thorpe, P.E. 1985. Preparation of antibody
Generation of Antibody Molecules Through Antibody Engineering
Twenty-five years ago, Georges K�hler and C�sar Milstein invented a means of cloning individual antibodies, thus opening up the way for tremendous advances in the fields of cell biology and clinical diagnostics ( 1 ). However, in spite
Recent Developments in Antibody Engineering
to the antibody’s N-terminus (1 ,2 ). These findings allowed scientists to transfer the principles of the immune system for producing specific antibodies to a given antigen into a bacterial system (3 ). It was now possible to establish antibody libraries in E
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