OPRD1 / Delta Opioid Receptor

分子量：
40kDa
细胞定位：
Antigen Cellular Localization: Cell membrane; Multi- pass membrane protein
形式：
Liquid
参考文献：
Knapp R.J.,et al.Life Sci. 54:PL463-PL469(1994). Knapp R.J.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. Simonin F.,et al.Mol. Pharmacol. 46:1015-1021(1994). Kaighin V.A.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. Gregory S.G.,et al.Nature 441:315-321(2006).
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OPRD1 / Delta Opioid Receptor antibody (C-Terminus).
功能：
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
总结：
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
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