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ACTH (Adrenocorticotrophic Ho

rmone) (Pituitary Marker) Antibody - Without BSA and Azide
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  • $495
  • Leading Biology
  • United States
  • 2025年07月16日
  • Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Mouse / IgG1, kappa

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 克隆性

      单克隆

    • 库存

      100

    • 宿主

      Mouse

    • 规格

      100 μg

    分子量:
    ACTH is ~5kDa, and the POMC precursor is ~30kDa. The molecular weight of POMC depends upon isoform variation and post-translational modifications.
    细胞定位:
    Antigen Cellular Localization: Secreted.
    形式:
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
    参考文献:
    Hsu DW et. al. American Journal of Pathology, 1991, 138(4):897-909
    产品概述:
    We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) antibody - Without BSA and Azide.
    功能:
    ACTH stimulates the adrenal glands to release cortisol. Beta-endorphin and Met-enkephalin are endogenous opiates.
    总结:
    ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).ĀIt also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. ĀĀ
    联系方式:

    生物商城:http://www.annoron.com

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    图标文献和实验
    相关实验
    • Endocrine System

      . One example of complex feedback occurs through the hypothalamic-pituitary target organ axis. Secretion of the hypothalamic corticotropin-releasing hormone releases pituitary ACTH, which in turn stimulates adrenal cortisol secretion. Subsequently

    • (共享)免疫单词缩写及翻译

      receptor antibody 乙酰胆碱受体抗体 ACIF anti-complement immunofluorescent method 抗补体免疫荧光法 α-1-ACt alpha(α)-1-anti-chymotrypsin α-1-抗糜蛋白酶 ACTH adrenocorticotropin hormone 促肾上腺皮质激素 AD Alzheimer's disease 老年性痴呆 ADDC antibody dependent

    • Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum

      for making working standards; store reconstituted standard at −20°C Mouse osteocalcin antiserum (biotinylated osteocalcin, antibody specific for the C‐terminus), one 12‐ml vial

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