- $495
- Leading Biology
- United States
- APR14656G
- 2025年09月03日
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse / IgG1, kappa
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 克隆性：
单克隆
- 库存：
100
- 宿主：
Mouse
- 抗体名：
HSP60
- 规格：
7 ml
60kDa
细胞定位：
Antigen Cellular Localization: Mitochondrion matrix.
形式：
Liquid. In PBS containing 0.02% sodium azide.
参考文献：
Boog CJ; de Graeff-Meeder ER; Lucassen MA; van der Zee R; Voorhorst-Ogink MM; van Kooten PJ; Geuze HJ; van Eden W. Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis. Journal of Experimental Medicine, 1992, 175(6):1805-10
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) antibody.
功能：
Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
总结：
Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp�s), more appropriately called as stress response proteins (srp�s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.
联系方式：
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文献和实验RT-PCR Quantitation of HSP60 mRNA Expression
Heat shock protein 60 (HSP60, HSPD1) is a “chaperonin” that facilitates folding of nascent proteins into proper conformations (1 ). It is thought to play a critical role in the assembly, folding, and transport of proteins in the mitochondria
Molecular chaperones or heat-shock proteins (HSPs) are protein machines that interact with unfolded or partially folded polypeptides and assist them in attaining their proper conformation. The folding reaction relies on a complex array
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人热休克蛋白60 ( HSP60 )ELISA 试剂盒 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 HSP60 单抗包被于酶标板上，标准品和样品中的 HSP60与单抗结合，加入生物素化的抗人 HSP60 ，形成免疫复合物连接在板上，辣根
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