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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 库存:
100
- 宿主:
Rabbit
- 抗体名:
BSP1, MADH1, MADR1
- 规格:
100 μl
52260 Da
细胞定位:
Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane
形式:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
参考文献:
Riggins G.J.,et al.Nat. Genet. 13:347-349(1996). Liu F.,et al.Nature 381:620-623(1996). Hoodless P.A.,et al.Cell 85:489-500(1996). Lechleider R.J.,et al.J. Biol. Chem. 271:17617-17620(1996). Zhang Y.,et al.Nature 383:168-172(1996).
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Smad1 (Phospho-Ser465) antibody.
功能:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
总结:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
联系方式:
生物商城:http://www.annoron.com
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官方售后:400-965-8633
企业 QQ:3212874516、3198592576
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