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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of rat connexin 43.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
Ck, D, H, M Mk, Sh, X, Zf, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of rat connexin 43.
- 目录编号:
253124
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
Connexin 43
- 抗体英文名:
Connexin 43 Antibody
- 抗体名:
Connexin 43 Antibody
- 规格:
0.1 ml
Connexin 43 Antibody产品详细介绍:
| 产品名称: | Connexin 43 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253124 |
| 规格: | 0.1 ml |
| 产品描述: | Connexin-43 (Gap junction alpha-1 protein, GJA1) forms connexons at cell gap junctions through which materials of low MW diffuse from one cell to a neighboring cell. Connexin-43 has a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Connexons are composed of a hexamer of connexins. Connexin-43 is expressed in the heart and fetal cochlear. Defects in Connexin-43 are the cause of autosomal dominant oculodentodigital dysplasia (ODDD), a serious condition of cranofacial anomalies, ocular defects and sometimes deafness and cardiac abnormalities. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of rat connexin 43. |
| 适用物种: | Ck, D, H, M Mk, Sh, X, Zf, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:1,000 |
| 别名: | Connexin-43; Gap junction alpha-1 protein; Cx43; Gap junction 43 kDa heart protein; GJA1; GJAL |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Analysis of Connexin 43 Expression on Keratinocytes Using Flow Cytometry
of differentiation. Quantitative data for the differential expression of epitopes on single cells can be obtained using a flow cytometer. Simultaneous analysis of two intracellular epitopes, keratin 14 and connexin 43, using flow cytometry after keratinocyte
five connexin family members have been linked to various types of skin diseases that appear to offset the balance between keratinocyte differentiation and proliferation. Consequently, in order to determine how these connexin gene mutations manifest as skin
The Use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Alterations in Connexin43 (Cx43) expression levels have been shown to play a role in inflammatory processes including skin wounding and neuroinflammation. Cx43 protein levels increase following a skin wound and can inhibit wound healing
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