重组人热反应蛋白12(HRSP12)北京现货

特别提示：包括重组人热反应蛋白12(HRSP12)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人热反应蛋白12(HRSP12)
英文名称：Recombinant Human Heat-Responsive Protein 12
产品货号：JN2026
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu137在N端含有His标签。

HRSP12质量控制：＞95%(还原性SDS-PAGE)

HRSP12制剂：液体

HRSP12保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于HRSP12：
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.

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