重组人IL-5北京价格

特别提示：包括重组人IL-5在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人IL-5
英文名称：Recombinant Human Interleukin-5
产品货号：GS4855
产品规格：2μg

分子量：Approximately 13.3kDa,a single non-glycosylated polypeptide chain containing 116 amino acids.
储存条件：冷冻（-20℃）

概述

The IL-5 gene is located on chromosome 5 in humans,in close proximity to the genes encoding IL-3,IL-4,and granulocyte-macrophage colony-stimulating factor(GM-CSF),which are often co-expressed in TH2 cells.Through binding to the IL-5 receptor,IL-5 stimulates B cell growth and increases immunroglobulin secretion.It is also a key mediator in eosinophil activation.Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.IL-5 is a 115-amino acid(in human,133 in the mouse)-long TH2 cytokine that is part of the hematopoietic family.Unlike other members of this cytokine family(namely IL-3 and GM-CSF),this glycoprotein in its active form is a homodimer.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1ng/ml,corresponding to a specific activity of>1.0×107 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.5,3%trehalose,0.1%Tween-80.
内毒素	Less than 1 EU/μg of rHuIL-5 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

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