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- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1579965-12-0
- 规格：
1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 1 mg | 产品价格： | ￥569.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1331.0 |
| 规格： | 10 mg | 产品价格： | ￥1933.0 |
| 规格： | 25 mg | 产品价格： | ￥3383.0 |
| 规格： | 50 mg | 产品价格： | ￥4804.0 |
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GSK2983559 free acid
CAS No. : 1579965-12-0
MCE 国际站：GSK2983559 free acid
产品活性：GSK2983559 free acid (compound 3) 是一种具有口服活性且高效的受体相互作用蛋白 2 (RIP2) 激酶抑制剂。GSK2983559 free acid 在体内和人类炎症性肠病外植体样本中可阻断多种促炎细胞因子反应活性。
研究领域：Apoptosis
作用靶点：RIP kinase
In Vitro: GSK2983559 (1-1024 nM; 2 h) blocks MDP-induced IL-8 in THP-1 cells.
In Vivo: GSK2983559 (oral gavage; 3 and 10 mg/kg; once) inhibits effectively MDP-induced IL-6 in mouse.
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文献和实验-3 have been identifiedand this list is growing. Chemical structure, potency, and otherfeatures of GSK-3 inhibitors have been extensively reviewed (12 –14) . Due to the high amino acid sequence homology of GSK-3aand GSK-3b kinase domains, no pharmacological inhibitors ofGSK
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
3b, while Wnts have so far onlybeen shown to regulate GSK3b (12) . Therefore the measurementof GSK3 activity in cells must take these differences into account. There are several approaches available to measure GSK3activity in cells, however the approach chosen
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠糖原合成酶激酶 3(GSK-3)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 GSK-3 单抗包被于酶标板上，标准品和样品中的 GSK-3 与单抗结合，加入生物素化的抗大鼠 GSK-3 ，形成免疫
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