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氢-钾ATP酶(H+、K+-ATPase)试剂盒

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  • 询价
  • 上海一研
  • EY-23324
  • 进口、国产
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      21

    • 英文名

      H+、K+-ATPase assay kit

    • 保质期

      详见说明书

    • 供应商

      上海一研

    • 保存条件

      低温

    • 规格

      200管/96样|100管/48样

    -钾ATP酶(H+、K+-ATPase)试剂盒 细胞生物学研究有以下几个方面:
    细胞生物学的研究内容十分广泛,主要包括:
    ①细胞核、染色体以及基因表达的研究;
    ②生物膜与细胞器的研究;
    ③细胞骨架体系的研究;
    ④细胞增殖及其调控;
    ⑤细胞分化及其调控;
    ⑥细胞的衰老与编程性死亡(凋亡);
    ⑦细胞的起源与进化;
    ⑧细胞工程.
    细胞生物学研究的常用技术有哪些:
    1.显微技术:包括显微观察,显微操作.
    2细胞组分分析技术:离心分离技术,生物大分子定位技术,定量细胞化学分析技术.
    3.细胞工程:细胞培养。
    以下是细胞生物学试剂的详细介绍:

    产品细节图片1
     中文名称:-钾ATP酶(H+、K+-ATPase)试剂盒  
    英文名称:H+、K+-ATPase assay kit

    产品规格:200管/96样|100管/48样
    发货周期:1~3天
    检测指标:氢-钾ATP酶;H+、K+-ATPase
    本试剂盒可测各种动物组织、培养细胞等样本中的H+K+-ATP酶活力。H+K+-ATPase对胃酸的分泌及胃的消化功能具有重要的生理意义,70年代Forte等人首先在牛蛙的胃粘膜上分离出一类能被K+专一激活而不被乌本苷抑制的ATPase即H+K+-ATPase,随后Lee·j等人又证明了含有该酶的膜囊泡运动跨膜运输质子的作用,从而为胃酸分泌的机理奠定了分子学基础,H+K+-ATPase定位于胃粘膜壁细胞(Parietal lell)上,属于第二类质子泵,它通过自身的磷酸化(E1→E2)与去磷酸化(E2→E1)完成的H+/K+电中性(electroneutral)跨膜离子转运,不断将壁细胞内的质子运输到膜外行使泌酸的功能。
    ATP酶可分解ATP生成ADP及无机磷,测定无机磷的量可判断ATP酶活力的高低。H+K+—ATP酶是一种能被钾专一激活而不被乌本苷抑制的ATP酶。
    优点如下:
    1、快速简便:全程约50分钟,可测100例左右样本。
    2、取样量微:本法取样本量100ul。
    3、稳定性好:试剂盒2~8℃存放6个月有效。
    4、再现性好:变异系数CV=1.7%。
    5、回收试验: X =103.3%。
    6、受外界影响因素小:干扰因素少,重复性强。
    7、测试面广:可测动物组织、红细胞以及各种培养细胞、各种水产等,效果均佳。
    产品细节图片2

    注意事项:
    1. 本试剂盒的检测试剂中含有萤光素酶,反复冻融会导致其逐渐失活。尽管经测试本试剂反复冻融5次对于其检测效果无显著影响,为取得良好的使用效果,*次解冻后可适当分装保存。反复冻融过程中,可能会导致检测试剂中出现少量沉淀,此时宜平衡至室温,并尽量溶解。如仍有残留的不溶物,可以离心去除后使用,经测试不会影响后续的检测效果。
    2. 检测时需使用白色或黑色的96孔板或384孔板。如果使用普通透明的96孔板或384孔板,相邻孔之间会产生相互干扰。
    3. 使用说明中提供了检测ATP标准品的方法,实际检测细胞活力时通常并不需要检测ATP标准品。

    产品细节图片3
    Dobrava-Belgrade Virus贝尔格莱德病毒型PCR试剂盒别    名  CD168; CD168 antigen; HMMR; HMMR_HUMAN; Hyaluronan mediated motility receptor; Hyaluronan-mediated motility receptor (RHAMM); IHABP; Intracellular hyaluronic acid-binding protein; Intracellular hyaluronic acid-binding protein; MGC119494; MGC119495; Receptor for hyaluronan-mediated motility; RHAMM; Hyaluronan mediated motility receptor.亚    型  IgG产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    Dobrava-Belgrade Virus贝尔格莱德病毒型染料法荧光定量PCR试剂盒别    名  C21orf55; C21orf78; DnaJ (Hsp40) homolog subfamily C member 28; DJC28_HUMAN .免 疫 原  KLH conjugated synthetic peptide derived from humna C21orf55产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Dobrava-Belgrade Virus贝尔格莱德病毒型探针法荧光定量PCR试剂盒别    名  C4orf32; CD032_HUMAN; Chromosome 4 open reading frame 32; FLJ39370; Uncharacterized protein C4orf32.免 疫 原  KLH conjugated synthetic peptide derived from human C4orf32产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Adenovirus鸭腺病毒PCR试剂盒别    名  Hypothetical protein LOC10826; Chromosome 5 open reading frame 4; FLJ13758; CE004_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C5ORF4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Adenovirus鸭腺病毒染料法荧光定量PCR试剂盒别    名  C4orf44; CD044_HUMAN; hypothetical protein LOC345222; Uncharacterized protein C4orf44.免 疫 原  KLH conjugated synthetic peptide derived from human C4orf44产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Adenovirus鸭腺病毒探针法荧光定量PCR试剂盒别    名  C4orf33; C4orf33 chromosome 4 open reading frame 33; CD033_HUMAN; UPF0462 protein C4orf33.免 疫 原  KLH conjugated synthetic peptide derived from human C4orf33产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Enteritis Virus鸭肠炎病毒PCR试剂盒别    名  Chromosome 5 open reading frame 20; DCNP1; Dendritic cell nuclear protein 1; DCNP1_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C5orf20产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Enteritis Virus鸭肠炎病毒染料法荧光定量PCR试剂盒别    名  Bcl10 interacting protein with CARD protein; BinCARD; Chromosome 9 open reading frame 89; BINCA_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C9orf89产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Enteritis Virus鸭肠炎病毒探针法荧光定量PCR试剂盒别    名  C8orf4; CH004_HUMAN; Chromosome 8 open reading frame 4; Human thyroid cancer 1; MGC22806; TC-1; TC1; Thyroid cancer protein 1; Uncharacterized protein C8orf4.免 疫 原  KLH conjugated synthetic peptide derived from human C8orf4产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus cccDNA(DHBV cccDNA)鸭乙型肝炎病毒cccDNA PCR试剂盒别    名  Uncharacterized protein C22orf25; chromosome 22 open reading frame 25; DKFZp 761 P 1121; Hypothetical protein LOC128989; TNG2_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C22orf25产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus cccDNA(DHBV cccDNA)鸭乙型肝炎病毒cccDNA 染料法荧光定量PCR试剂盒别    名  C20orf196; CT196_HUMAN; Uncharacterized protein C20orf196.免 疫 原  KLH conjugated synthetic peptide derived from human C20orf196产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus cccDNA(DHBV cccDNA)鸭乙型肝炎病毒cccDNA 探针法荧光定量PCR试剂盒别    名  C21orf14; C21orf38; C21orf7; Chromosome 21 open reading frame 38; Chromosome 21 open reading frame 91; Early undifferentiated retina and lens; EURL; Protein EURL homolog; YG81; EURL_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human EURL/C21orf91产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus(DHBV)鸭乙型肝炎病毒PCR试剂盒别    名  chromosome 6 open reading frame 192; hypothetical protein LOC116843; Uncharacterized MFS-type transporter C6orf192; S18B1_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C6orf192产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus(DHBV)鸭乙型肝炎病毒染料法荧光定量PCR试剂盒别    名  chromosome 21 open reading frame 87; BRIT2_HUMAN.免 疫 原  KLH conjugated synthetic peptide derived from human C21orf87产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    Duck Hepatitis B Virus(DHBV)鸭乙型肝炎病毒探针法荧光定量PCR试剂盒别    名  CAD18_HUMAN; Cadherin 14; Cadherin14; Cadherin 18; Cadherin18; Cadherin 18, type 2; Cadherin-14; Cadherin-18; CDH14; CDH14L; CDH18; CDH24; EY CADHERIN.免 疫 原  KLH conjugated synthetic peptide derived from human CDH18产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500亚    型  IgG纯化方法  affinity purified by Protein A储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    TRH  促甲状腺素释放激素抗体Rhesus antibody Rh规格 0.1ml

    TRF2  端粒结合蛋白2抗体Rhesus antibody Rh规格 0.1ml
    TReP132/RAPA  乳腺癌抗雌激素抵抗蛋白2抗体Rhesus antibody Rh规格 0.2ml
    TREML2/TLT2  髓系细胞触发受体样转录因子2抗体Rhesus antibody Rh规格 0.2ml
    TREML1/TLT1  髓系细胞触发受体样转录因子1抗体Rhesus antibody Rh规格 0.2ml
    -钾ATP酶(H+、K+-ATPase)试剂盒 ABCG1  三磷腺苷结合盒亚家族G1抗体 50次Radix saposhnikoviae防风PCR鉴定试剂盒    20度 一年2-4周 低温

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    Endomucin  内皮粘蛋白EMCN抗体进口/国产小鼠基质金属蛋白酶1(MMP-1)ELISA Kit,48T/96T
    KLK3/Prostate Specific Antigen  激肽释放酶3/舒血管素3抗体进口/原装大鼠基质金属蛋白酶1(MMP-1)ELISA Kit,48T/96T
    氧化低密度脂蛋白抗体检测试剂盒中药对照药材进口/原装磺胺吡标准品磺胺吡标准品48T/96T特价供应规格:
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    Newcastle disease virus  鸡新城疫疫苗(鸡瘟4型混合病)抗体特价促销人基质金属蛋白酶10(MMP-10)ELISA Kit,48T/96T
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    •  代谢紊乱

      血症,又可导致低氯血症。已经证明,任何原因引起的低氯血症均可使肾排增多。其可能机制之一是低氯血症似能直接剌激远侧肾小管的泌功能。 ②某些肾脏疾病:如远侧肾小管性酸中毒时,由于远曲小管泌功能障碍,因而H+-Na+交换减少而K+-Na+交换增多而导致失。近侧肾小管性酸中毒时,近曲小管HCO3-的重吸收减少,到达远曲小管的HCO3-增多是促进远曲小管排增多的重要原因(详后文)。急性肾小管坏死的多尿期,由于肾小管液中尿素增多所致的渗透性利尿,以及新生肾小管上皮对水、电解质重吸收的功能不足

    • 氧化磷酸化抑制剂

      ,DCC)可与F0的DCC结合蛋白结合,阻断H+通道,抑制ATP合成。栎皮酮(quercetin)直接抑制参与ATP合成的ATP酶。 (三)解偶联剂(uncoupler) 解偶联剂使氧化和磷酸化脱偶联,氧化仍可以进行,而磷酸化不能进行,解偶联剂作用的本质是增大线粒体内膜对H+的通透性,消除H+的跨膜梯度,因而无ATP生成,解偶联剂只影响氧化磷酸化而不干扰底物水平磷酸化,解偶联剂的作用使氧化释放出来的能量全部以热的形式散发。动物棕色脂肪组织线粒体中有独特的解偶联蛋白,使氧化磷酸化处于解偶联状态

    • 血症

      。许多利尿药还有一个引起肾排增多的共同机制:通过血容量的减少而导致醛固酮分泌增多。速尿、利尿酸、噻嗪类的作用在于抑制髓袢升支粗段对Cl-的重吸收从而也抑制了Na+的重吸收。所以,这些药物的长期使用既可导致低钠血症,又可导致低氯血症。已经证明,任何原因引起的低氯血症均可使肾排增多。其可能机制之一是低氯血症似能直接剌激远侧肾小管的泌功能。 ②某些肾脏疾病:如远侧肾小管性酸中毒时,由于远曲小管泌功能障碍,因而H+-Na+交换减少而K+-Na+交换增多而导致失。近侧肾小管性酸中毒时

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