产品货号:jlcR17149 英文名称:TRNT1 中文名称:TRNT1蛋白抗体 别 名:AA408384; C76540; CCA adding; CCA1; CGI 47; EC 2.7.7.25; Mitochondrial CCA adding tRNA nucleotidyltransferase; Mitochondrial tRNA nucleotidyl transferase, CCA adding; mt CCA adding enzyme; mt Trat; mt tRNA adenylyltransferase; mt tRNA CCA diphosphorylase; mt tRNA CCA pyrophosphorylase; MtCCA; MTO2; TRNT1_HUMAN; TRMU; tRNA nucleotidyl transferase; tRNA nucleotidyl transferase CCA adding 1. 研究领域:细胞生物 转录调节因子 表观遗传学 抗体来源:Rabbit 克隆类型:Polyclonal 交叉反应: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 产品应用:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量:45kDa 细胞定位:细胞浆 性 状:Lyophilized or Liquid 浓 度:1mg/ml 免 疫 原:KLH conjugated synthetic peptide derived from human TRNT1:351-434/434 亚 型:IgG 纯化方法:affinity purified by Protein A 储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed:PubMed 产品介绍:The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM, Aug 2009]
Function: TRNT1 belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. It adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates.
Subunit: Monomer, and homodimer; disulfide-linked.
Subcellular Location: Mitochondrial
Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
SWISS: Q96Q11
Gene ID: 51095
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.