重组大鼠HB-EGF北京现货

特别提示：包括重组大鼠HB-EGF在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠HB-EGF
英文名称：Recombinant Rat Heparin-binding EGF-like Growth Factor
产品货号：GS4714
产品规格：10μg

分子量：Approximately 9.7kDa,a single non-glycosylated polypeptide chain containing 86 amino acids.
储存条件：冷冻（-20℃）

概述

Heparin-binding epidermal growth factor(HB-EGF)-like growth factor(EGF)is found in cerebral neurons.Its expression is increased after hypoxic or ischemic injury,which also stimulates neurogenesis.HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing,and in pathological processes such as tumor growth,SMC hyperplasia and atherosclerosis.HB-EGF is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues.In addition,it shares about 73%and 76%a.a.sequence identity with murine and rat HB-EGF.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml,corresponding to a specific activity of>1.0×106 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,300mMNaCl,pH 7.4,5%trehalose.
内毒素	Less than 1 EU/μg of rRtHB-EGF as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	DLEGTDLDLF KVAFSSKPQA LATPGKEKNG KKKRKGKGLG KKRDPCLKKY KDYCIHGECR YLKELRIPSC HCLPGYHGQR CHGLTL

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