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Recombinant Human Cadherin-3/C

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  • 询价
  • 上海谷研
  • GOY-9749
  • 进口、国产
  • 2025年07月12日
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      上海谷研

    • 库存

      31

    • 规格

      10ug

    公司供应的产品仅用于科研
    产品名称:Recombinant Human Cadherin-3/CDH3
    Known as    Cadherin-3; Placental Cadherin; P-Cadherin; CDH3; CDHP
    Derived from    Human Cells
    Purity    Greater than 95% as determined by reducing SDS-PAGE.
    Formulation    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    Shipping    The product is shipped at ambient temperature.
    Storage    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
    Reconstitution    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Endotoxin    Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
    Background    Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
    Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654 is expressed with a 6His tag at the C-terminus.
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