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产品名称：Recombinant Human BDNF/Brain-derived neurotrophic factor
Known as Brain-Derived Neurotrophic Factor; BDNF; Abrineurin
Derived from E.coli
Purity Greater than 95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Shipping The product is shipped at ambient temperature.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Background Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.
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MCHR1 Polyclonal Antibody 黑色素聚集激素受体1 抗体
MRAP Polyclonal Antibody 黑皮质素2受体辅助蛋白2 抗体
IMA1 Polyclonal Antibody 核转运蛋白A1 抗体
NFX1 Polyclonal Antibody 核转录因子X1 抗体
NFATc2 Polyclonal Antibody 核因子活T细胞胞浆蛋白2 抗体
NFIX Polyclonal Antibody 核因子I/X 抗体
Recombinant Human BDNF/Brain-derived neurotrophic factorNFE2 Polyclonal Antibody 核因子(网织红细胞衍生2),45kDa 抗体
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Anti-Lamin B1 Monoclonal Antibody (15T1) , HRP Conjugated 核纤层蛋白B1单克隆抗体(15T1) , HRP偶联
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文献和实验Production of Recombinant Neurotrophic Factors
factor (NGF), and its related protein family members, brainderived neurotrophic factor (BDNF or NT-2), and neurotrophin3 (NT.-3). The potential of producing mg and larger quantities of these agents will expedite our understanding of their functions
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
Expression of Neurotrophic Factors such as GDNF in the E. coli System
Neurotrophic factors play an essential role in the growth, survival, and differentiation of neurons in the nervous system. Several well-characterized neurotrophic factors, such as nerve growth factor (NGF), brain-derived
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