- 询价
- Cell Signaling Technology
- 3329
- USA
- 2026年01月06日
- W, IF-IC, F
- H
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
MNDA (3C1) Rat mAb
- 抗原：
nuclear extract from human granulocytes
- 应用范围：
W, IF-IC, F
- 级别：
详见MSDS文件
- 库存：
大量
- 适应物种：
H
- 供应商：
CST
- 保质期：
详见说明书
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IF-IC=Immunofluorescence (Immunocytochemistry) F=Flow Cytometry
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W IF-IC F | H | Endogenous | 50 | Rat IgG1 |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | MNDA (3C1) Rat mAb detects endogenous levels of total MNDA protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with nuclear extract from human granulocytes. Western Blotting
Western blot analysis of extracts from HL-60 and THP-1 cells using MNDA (3C1) Rat mAb. Flow Cytometry
Flow cytometric analysis of Jurkat cells (red) and THP-1 cells (blue) using MNDA (3C1) Rat mAb. IF-IC
Confocal immunofluorescent analysis of THP-1 cells (left) and Jurkat cells (right) using MNDA (3C1) Rat mAb (green). Actin filaments were labeled with DY-554 phalloidin (red). |
| Background | MNDA (myeloid cell nuclear differentiation antigen) is a transcription factor constitutively expressed in peripheral blood granulocytes and monocytes; low expression is also found in a subset of B cells (1,2). MNDA is a member of the interferon (IFN)-regulated 200 family of genes, which contain one or more copies of a partially conserved domain of 200 amino acid residues thought to mediate protein-protein interaction (3). MNDA may play a role in apoptosis and its expression is reduced in myelodysplastic syndromes (MDS) (4). MNDA has been proposed to be a marker for nodal marginal zone lymphoma (5). |
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验Immunofluorescent Staining of Mouse and Rat Leukocytes
mAb. It is important to verify that no secondary reagent will bind the BD Fc Block™. Please see description in "The Uses of BD Fc Block™ in Immunophenotyping of Mouse and Rat Leukocytes". For very low-density cell surface markers (e.g.,cytokine
Notes on Making Rat x Y3 Monoclonal Antibody Producing Hybridomas
Although Y3/Ag1.2.3 has its own myeloma light chain, their are numerous characteristics that make this a better parent line for making hybridomas than the 'Y0' chain loss variants or using NS0 to make rat x mouse hybrids. These are: a) Hybridomas
Dual- and Triple-Color Fluorospot
in the analysis, e.g., IL-10, rat mAb 9D7 is used for coating and tag (different from FITC and biotin)-labeled rat mAb 12G8 is used for detection. All mAbs from Mabtech, Nacka Strand, Sweden. 4. Secondary reagents for amplification: Mouse anti-FITC mAb
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