- 询价
- Cell Signaling Technology
- 3243
- USA
- 2025年07月15日
- W
- H,M,Mk
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- 详细信息
- 技术资料
- 抗体英文名：
LAMP1 (C54H11) Rabbit mAb
- 抗原：
synthetic peptide surrounding Ser140 of human LAMP1
- 应用范围：
W
- 适应物种：
H,M,Mk
- 库存：
大量
- 级别：
详见MSDS文件
- 保质期：
详见说明书
- 供应商：
CST
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse Mk=Monkey
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W | H M Mk | Endogenous | 42 (non-glycosylated), 90-120 (glycosylated) | Rabbit IgG |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | LAMP1 (C54H11) Rabbit mAb detects endogenous levels of total LAMP1 protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Ser140 of human LAMP1. Western Blotting
Western blot analysis of extracts from HeLa, Neuro2a and COS cells using LAMP1 (C54H11) Antibody. |
| Background | LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis (3). The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes (4). LAMP1 and LAMP2 are 37% homologous in their protein sequences. The cellular functions of these two proteins are also overlap - both are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking (5,6).
|
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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