- 询价
- Cell Signaling Technology
- 4253
- USA
- 2025年12月12日
- W
- Rabbit
- H
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
GATA-6 (A549) Antibody
- 抗原：
synthetic peptide corresponding to amino acid sequence surrounding Ala549 of human GATA-6 protein
- 应用范围：
W
- 宿主：
Rabbit
- 保质期：
详见说明书
- 适应物种：
H
- 级别：
详见MSDS文件
- 供应商：
CST
- 库存：
大量
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H | Endogenous | 55 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | GATA-6 (A549) Antibody detects endogenous levels of total GATA-6 protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acid sequence surrounding Ala549 of human GATA-6 protein. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from Huh7, KM12 and 293 cells using GATA-6 (A549) Antibody. |
| Background | GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA binding domains, which bind directly to the nucleotide sequence core element GATA (1-3). There are six vertebrate GATA proteins, designated GATA-1 to GATA-6 (3). GATA-6 plays a critical role in endoderm development (4). It is essential for development of the heart, gut and other organs (5,6). Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm (4). Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors (7).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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人转录因子GATA 结合蛋白 3 ( GATA-3 )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 GATA-3 单抗包被于酶标板上，标准品和样品中的 GATA-3与单抗结合，加入生物素化的抗人 GATA-3 ，形成免疫复合物连接在板上，辣根过氧化物酶标记的 Streptavidin 与生物素结合，加入
secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
「癌细胞」：是我杀了我？PNAS 这项研究竟让肿瘤自己杀死自己
保障，使其无法成为标准治疗方法。 那么是否能够在肿瘤内产生生物制剂，随后扩散并在局部发挥作用呢？ 2021 年 5 月 17 日，苏黎世大学 Andreas Plückthun 团队在 PNAS 上发表题为 The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody 的研究论文。 图片来源
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