- 询价
- Cell Signaling Technology
- 2173
- USA
- 2025年10月28日
- W, IP, IHC-P
- H,M,R
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- 详细信息
- 技术资料
- 抗体英文名：
Calbindin (C26D12) Rabbit mAb
- 抗原：
synthetic peptide corresponding to residues surrounding amino acid 200 of human calbindin
- 应用范围：
W, IP, IHC-P
- 库存：
大量
- 保质期：
详见说明书
- 供应商：
CST
- 级别：
详见MSDS文件
- 适应物种：
H,M,R
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W IP IHC-P | H M R | Endogenous | 28 | Rabbit IgG |
| Protocols | |
|---|---|
| Specificity / Sensitivity | Calbindin (C26D12) Rabbit mAb detects endogenous levels of total calbindin protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding amino acid 200 of human calbindin. Western Blotting
Western blot analysis of extracts from mouse and rat brain using Calbindin (C26D12) Rabbit mAb. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded mouse cerebellum using Calbindin (C26D12) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right). |
| Background | Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, paravalbumin and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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