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Oct-1 (D7B6) Rabbit mAb

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年10月17日
  • W, IP
  • H
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体英文名

      Oct-1 (D7B6) Rabbit mAb

    • 抗原

      synthetic peptide corresponding to residues surrounding Ala367 of human Oct-1 protein

    • 应用范围

      W, IP

    • 适应物种

      H

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 保质期

      详见说明书

    • 供应商

      CST

    • 是否单克隆

      1

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Isotype
    W IP H Endogenous 90 Rabbit IgG
    Protocols
    Specificity / Sensitivity

    Oct-1 (D7B6) Rabbit mAb recognizes endogenous levels of total Oct-1 protein.

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala367 of human Oct-1 protein.

    Western Blotting

    Western Blotting

    Westerrn blot analysis of extracts from various cell lines using Oct-1 (D7B6) Rabbit mAb.

    Background

    Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain (1). Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc (2), OBF-1 (a B-cell transcriptional coactivator protein) (3), TFIIB (4), and TBP (TATA-box-binding protein) (5). Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development (6).

    1. Sturm, R.A. et al. (1988) Genes Dev 2, 1582-99.
    2. Mittal, V. et al. (1996) Mol Cell Biol 16, 1955-65.
    3. Strubin, M. et al. (1995) Cell 80, 497-506.
    4. Nakshatri, H. et al. (1995) J Biol Chem 270, 19613-23.
    5. Zwilling, S. et al. (1994) Nucleic Acids Res 22, 1655-62.
    6. Schonemann, M.D. et al. (1998) Adv Exp Med Biol 449, 39-53.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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