- 询价
- Cell Signaling Technology
- 8144
- USA
- 2025年10月16日
- W
- Rabbit
- H,M
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- 详细信息
- 技术资料
- 抗体英文名：
PDLIM2 Antibody
- 抗原：
synthetic peptide corresponding to residues surrounding Gly255 of human PDLIM2 protein
- 应用范围：
W
- 宿主：
Rabbit
- 库存：
大量
- 级别：
详见MSDS文件
- 供应商：
CST
- 适应物种：
H,M
- 保质期：
详见说明书
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H M | Endogenous | 38 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | PDLIM2 Antibody recognizes endogenous levels of total PDLIM2 protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly255 of human PDLIM2 protein. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from various cell lines and mouse lung using PDLIM2 Antibody. Western Blotting
Western blot anlysis of extracts from 293T cells, mock transfected (-) or transfected with a human PDLIM2 construct (hPDLIM2, +), using PDLIM2 Antibody. |
| Background | PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration (1,2). Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65 (3). PDLIM2 is suppressed in cancer cell lines by DNA methylation (4,5). Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation. |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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