- 询价
- Cell Signaling Technology
- 2093
- USA
- 2025年10月15日
- W, IHC-P, F
- H
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- 详细信息
- 技术资料
- 抗体英文名：
SCF (C19H6) Rabbit mAb
- 抗原：
synthetic peptide corresponding to amino acids in the N-terminal sequence of human SCF
- 应用范围：
W, IHC-P, F
- 级别：
详见MSDS文件
- 供应商：
CST
- 库存：
大量
- 适应物种：
H
- 保质期：
详见说明书
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IHC-P=Immunohistochemistry (Paraffin) F=Flow Cytometry
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W IHC-P F | H | Endogenous | 18 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | SCF (C19H6) Rabbit mAb detects endogenous levels of SCF by immunohistochemical staining and by flow cytometry. Western blotting detects recombinant SCF. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino acids in the N-terminal sequence of human SCF. Western Blotting
Western blot analysis of recombinant SCF (5 ng) using SCF (C19H6) Rabbit mAb. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using SCF (C19H6) RmAb. Flow Cytometry
Flow cytometric analysis of U-87 MG cells using SCF (C19H6) Rabbit mAb (blue) compared to a nonspecific negative control antibody (red). |
| Background | Stem cell factor (SCF) is a growth factor that is essential for hematopoiesis, melanogenesis and fertility. SCF is also known as mast cell growth factor (MCGF), steel factor (SLF), or kit ligand (KL) (1-3). SCF mediates its biological effects by binding to and activating c-Kit (4). SCF induces dimerization of c-Kit followed by trans-autophosphorylation of the cytoplasmic protein tyrosine kinase domain, leading to subsequent recruitment of signaling proteins, tyrosine phosphorylation of substrates and activation of multiple signaling pathways (5,6). SCF/c-Kit may take part in the growth control of human malignancies (7).
|
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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