Tyrosinase (T311) Mouse mAb (IHC Specific)

Tyrosinase (T311) Mouse mAb (I

HC Specific)
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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年10月12日
  • IHC-P
  • H
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Tyrosinase (T311) Mouse mAb (IHC Specific)

    • 抗原

      purified recombinant tyrosinase

    • 应用范围

      IHC-P

    • 适应物种

      H

    • 供应商

      CST

    • 库存

      大量

    • 级别

      详见MSDS文件

    • 保质期

      详见说明书

    • 是否单克隆

      0

    • 保存条件

      -20°c

    • 规格

      100 ul (50 sections)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (50 sections)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  IHC-P=Immunohistochemistry (Paraffin)
    Reactivity Key:  H=Human
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Isotype
    IHC-P H Endogenous 70-80 Mouse IgG2a
    Protocols

    * Product-specific protocol.

    Specificity / Sensitivity

    Tyrosinase (T311) Mouse mAb detects endogenous levels of total tyrosinase protein.

    Source / Purification

    Tyrosinase (T311) Mouse mAb is produced by immunizing animals with a purified recombinant tyrosinase.

    IHC-P (paraffin)

    IHC-P (paraffin)

    Immunohistochemical analysis of human colon tissue using Tyrosinase (T311) Mouse mAb (IHC Specific). Note the lack of staining in the tyrosinase negative tissue.

    IHC-P (paraffin)

    IHC-P (paraffin)

    Immunohistochemical analysis of human melanoma tissue using Tyrosinase (T311) Mouse mAb (IHC Specific).

    Background

    Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1).

    1. Chen, Y.T. et al. (1995) Proc Natl Acad Sci USA 92, 8125-9.
    2. Kwon, B.S. (1993) J Invest Dermatol 100, 134S-140S.
    3. Kwon, B.S. et al. (1987) Proc Natl Acad Sci USA 84, 7473-7.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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