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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
150 amino acid recombinant protein from N-term moiety of mouse PD-1.
- 亚型:
mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
150 amino acid recombinant protein from N-term moiety of mouse PD-1.
- 目录编号:
253279
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
PD-1 (12A7D7)
- 抗体英文名:
PD-1 (12A7D7) Antibody
- 抗体名:
PD-1 (12A7D7) Antibody
- 规格:
0.1 mg
PD-1 (12A7D7) Antibody产品详细介绍:
| 产品名称: | PD-1 (12A7D7) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253279 |
| 规格: | 0.1 mg |
| 产品描述: | Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of “danger signals” such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | mouse IgG1 |
| 免疫原: | 150 amino acid recombinant protein from N-term moiety of mouse PD-1. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:500-1:1,000; IHC: 1:100-1:500 |
| 别名: | PD-1; Programmed cell death 1; PDCD-1; CD279 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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