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ORAI3 (2H2G9) Antibody_ORAI3 (

2H2G9)抗体
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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 253272
  • 2025年07月13日
  • E, WB, IHC
  • Mouse
  • H, R
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ORAI3.

    • 亚型

      mouse IgG1

    • 形态

      Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.

    • 保存条件

      Store at 4°C.

    • 克隆性

      单克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H, R

    • 保质期

      1-2年

    • 抗原来源

      KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ORAI3.

    • 目录编号

      253272

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      Abbiotec

    • 宿主

      Mouse

    • 应用范围

      E, WB, IHC

    • 浓度

      见详细说明信息

    • 靶点

      ORAI3 (2H2G9)

    • 抗体英文名

      ORAI3 (2H2G9) Antibody

    • 抗体名

      ORAI3 (2H2G9) Antibody

    • 规格

      0.1 mg

    产品细节图片1
    ORAI3 (2H2G9) Antibody产品详细介绍:
    产品名称: ORAI3 (2H2G9) Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 253272
    规格: 0.1 mg
    产品描述: Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. Larger molecular weight bands are sometimes seen in SDS-PAGE; these may represent post-translationally modified ORAI 3.
    克隆类型: Mouse Monoclonal Antibody
    亚型: mouse IgG1
    免疫原: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ORAI3.
    适用物种: H, R
    应用范围: E, WB, IHC
    应用说明: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
    别名: ORAI3; Transmembrane protein 142C; TMEM142C; Calcium release-activated calcium channel protein 3
    形态: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
    保存条件: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
    参考文献:

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    产品细节图片2 产品细节图片3

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