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- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
J2
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2133499-85-9
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥4361.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥1500.0 |
| 规格： | 5 mg | 产品价格： | ￥3200.0 |
| 规格： | 10 mg | 产品价格： | ￥4800.0 |
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HSP27 inhibitor J2
CAS No. : 2133499-85-9
MCE 国际站：HSP27 inhibitor J2
产品活性：HSP27 inhibitor J2 (J2) 是一种 HSP27 抑制剂，其显著诱导异常 HSP27 二聚体形成并抑制 HSP27 巨聚合物的产生，从而具有抑制 HSP27 的伴侣功能和降低其细胞保护功能的作用。HSP27 inhibitor J2 (J2) 显著增强 17-AAG 的抗增殖活性，并对顺铂诱导的肺癌细胞生长抑制具有敏感性。
研究领域：Cell Cycle/DNA Damage | Metabolic Enzyme/Protease
作用靶点：HSP
In Vitro: HSP27 inhibitor J2 (10 μM; 12 h) induces significant abnormal HSP27 dimer formation in NCI-H460.
HSP27 inhibitor J2 (10 μM; 24 h) increases 17-AAG-induced apoptosis in shCTRL cells.
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