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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2113650-05-6
- 规格：
10 mM * 1 mL/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2530.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1930.0 |
| 规格： | 10 mg | 产品价格： | ￥3200.0 |
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BMS-1166 hydrochloride
CAS No. : 2113650-05-6
MCE 国际站：BMS-1166 hydrochloride
产品活性：BMS-1166 hydrochloride 是一种有效的 PD-1/PD-L1 免疫检查点抑制剂。BMS-1166 hydrochloride 诱导 PD-L1 二聚化并阻断其与 PD-1 的相互作用，IC50 为 1.4 nM。BMS-1166 hydrochloride 拮抗 PD-1/PD-L1 免疫检查点对 T 细胞活化的抑制作用。
作用靶点：PD-1/PD-L1
In Vitro: BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1.
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文献和实验Lacrimal Experimental Protocol (4/4/94)
3. Place BMS at 4°C and LM at 4°C. If not planning to use gelled substrate, coat at 4 - 8 µg/well in 100 µl of dH2O overnight at 4°C. Day of Experiment: 1. Thaw on ice STI , hyaluronidase , collagenase , DNase , dexamethasone , putrescine
SSR GEL and Silver Staining Protocol
5985 Highway K Rhinelander, WI 54501 USA Phone: 715-362-1121 Fax: 715-362-1166 e-mail: pmarquar@newnorth.net I. EQUIPMENT: II. MOLD ASSEMBLY: 1. Wash inner and outer plates well with alconox cleanser. Rinse well with tap water
SSR GEL and Silver Staining Protocol
Service Research 5985 Highway K Rhinelander, WI 54501 USA Phone: 715-362-1121 Fax: 715-362-1166 e-mail: pmarquar@newnorth.net I. EQUIPMENT: DNA sequencing unit (35 x 45 cm) & 2000V power supply Clamps Lg. plastic trays (4), about 43 x 50 x
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